Association·arcadia

Compound 48/80 is toxic to HMC1.2 and RBL-2H3 cells

Claim that compound 48/80, an MRGPRX2 agonist and common mast cell activator, is toxic to the human mast cell line HMC1.2 and the rat basophil line RBL-2H3 at concentrations typically used in degranulation assays.

Confidence
100%
active

Evidence Quote

Compound 48/80, an MRGPRX2 agonist and common mast cell activator, is toxic in HMC1.2 and RBL-2H3 cells

Relationship

Compound 48/80 treatment increases Toxicity in HMC1.2 and RBL-2H3 cells