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Toxicity in HMC1.2 and RBL-2H3 cells

Toxicological effect (cell lysis) observed in human HMC1.2 mast cells and rat RBL-2H3 basophil cell lines upon exposure to compound 48/80.

Confidence
90%
active

Source

Audrey Bell et al. (2025). Can compound 48/80 be used for safe mast cell degranulation assays? doi:10.57844/arcadia-3207-4695 ↗

Connections (2)

Compound 48/80 is toxic to HMC1.2 and RBL-2H3 cellsAssociation
No non-toxic activity window for 48/80 in HMC1.2 and RBL-2H3Association