Association·nasa

Stability of Luc reporter affects but does not fully explain off-kinetics

Modeling and simulation show that changing the degradation rate constant of luciferase impacts signal decline, but cannot fully account for slow off-kinetics observed experimentally.

Confidence
80%
active

Evidence Quote

Simulation of different luciferase stability affects output kinetics

Relationship

Luciferase reporter stability partially explains Slow LUC off kinetics