Association·nasa
Microgravity upregulates auxin signaling genes
In two spaceflight experiments, auxin-related genes including transporters, response factors, and small auxin upregulated genes were found to be upregulated in microgravity relative to 1g controls.
Confidence
90%
active
Evidence Quote
“Auxin transport and signaling genes, including PIN3, PIN4, multiple ARFs, and 11 SAUR genes, are upregulated in microgravity relative to 1 g controls.”
Relationship
microgravity increases auxin signaling genes
Connections (11)
Microgravity alters plant transcriptional networks via coordinated gene set regulationInferenceChain
Spaceflight alters plant gene expressionAssociation
Microgravity triggers coordinated transcriptional shifts impacting auxin signaling, vesicle transport, and stress response in leavesInferenceChain
Microgravity-driven coordination of auxin signaling and gravitropismInferenceChain
Transcription factor control coordinates SAUR gene expression and adaptive growthInferenceChain
Transcription factor coordination mediates gene network shifts in microgravityInferenceChain
Gene set analysis and annotation tools enable transcriptional network interpretation in spaceflight plant studiesInferenceChain
Organ- and layer-specific regulation of gene expression under spaceflightInferenceChain
Fractional gravity orchestrates root transcriptional adaptationInferenceChain
Crosstalk and regulatory networks coordinate plant stress responses in microgravityInferenceChain
Integration of TCP11, miR156/SPL, and HY5 in plant developmental regulationInferenceChain
Evidence
“Review of the roles of auxin response factors (ARFs) in auxin-regulated gene expression”
“Role of SAUR63 gene in promoting elongation of hypocotyls and stamen filaments in Arabidopsis”
(2012). Arabidopsis SMALL AUXIN UP RNA63 promotes hypocotyl and stamen filament elongation doi:10.1111/j.1365-313X.2012.05024.x ↗
“Comprehensive reannotation of the Arabidopsis reference genome (Araport11)”
(2017). Araport11: a complete reannotation of the Arabidopsis thaliana reference genome doi:10.1111/tpj.13415 ↗
“Study showing IDD14/15/16 promote lateral organ morphogenesis and gravitropism via auxin biosynthesis and transport.”
Cui, D. et al. (2013). The arabidopsis IDD14, IDD15, and IDD16 cooperatively regulate lateral organ morphogenesis and gravitropism by promoting Auxin biosynthesis and transport. doi:10.1371/journal.pgen.1003759 ↗
“Review on structure and function of auxin response factor (ARF) in plants.”
Li, Y. et al. (2023). Advances in structure and function of auxin response factor in plants doi:10.1111/jipb.13392 ↗