Microgravity downregulates stress response genes
Genes related to biotic and abiotic stress response, defense, calcium signaling, and cell wall organization are significantly downregulated in microgravity compared to 1g controls in spaceflight experiments.
Evidence Quote
“Genes involved in defense response, abiotic stress, Ca++ signaling, and cell wall modification were downregulated in microgravity in both datasets.”
Relationship
Arguments
Connections (9)
Evidence
“RNAseq study examining how Arabidopsis responds to partial gravity and blue light stimulation during spaceflight.”
“Reference for response of plant metabolism to hypoxia”
“Reference on cytosolic Ca2+ and gene expression response to gravitation in Arabidopsis”
“Reference on vacuolar protein degradation via autophagy as an adaptive response to sugar starvation in Arabidopsis.”
“Reference showing changes in cell wall organization and stress response in Arabidopsis seedlings during spaceflight.”
“Reference examining response of plant metabolism to hypoxia.”
“Reference reporting Arabidopsis cell culture responses (calcium, gene expression) to parabolic flight and altered gravitation.”
“Reference on the role of AINTEGUMENTA in regulating organ size in Arabidopsis.”
“Study on newly observed phototropic responses to red light in microgravity.”
“BMC Genomics study on Arabidopsis core promoter structure and function.”
“Study on microsome-associated proteome modifications in Arabidopsis on ISS, Plant Signaling & Behavior.”
“Study showing that CBF2/DREB1C negatively regulates other CBF/DREB genes and is central for stress tolerance.”
“Review on the regulation of transcription factors involved in plant defense signaling.”
“Review on WRKY transcription factors focusing on their molecular regulatory roles in plant stress responses”