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Mechanistic reasoning for red/far-red light-induced gene regulation in yeast

Explains how photoactivated phytochrome A, via red/far-red light, enables controlled recruitment of FHL/FHY1 fusion proteins, leading to switchable activation or deactivation of luciferase gene expression in yeast.

Confidence
80%
◑partialactivecomplexity: mid

Reasoning Steps (2)

Red light photoactivation of phytochrome promotes FHL/FHY1 protein recruitmentStep 1
External light input acts as reversible gene expression switchStep 2

Source

Synthesis for current paper

Connections (5)

Red light-induced interaction between PHYTOCHROME A and FHLAssociation
FHL-PhyA complex activates transcription via GAL1 promoterAssociation
Red light increases luciferase expressionAssociation
Light input controls phytochrome activity in yeastAssociation
Photoactivated phytochrome A regulates luciferase reporter in yeastAssociation