Association·arcadia

Subset of protein families show structural conservation despite sequence and phylogenetic diversity

A subset of protein families in Asgard archaea proteomes retain similar structural features even when sequences and phylogenetic positions are very different.

Confidence
90%
active

Evidence Quote

“Subset of protein families with structural conservation despite phylogenetic and sequence diversity”

Arguments

TM-score (structural similarity)subject

Connections (3)

Diversity of evolutionary strategies in Asgard protein sequence–structure relationshipsInferenceChain
Structural similarity often diverges from sequence similarityAssociation
Sequence–structure evolutionary diversity explained by methodological rigorInferenceChain

Evidence

“Citation for Kostlbacher et al. (2024) on protein structure inference of eukaryotic complexity in Asgard archaea.”

Köstlbacher S et al. (2024). Structure-based inference of eukaryotic complexity in Asgard archaea doi:10.1101/2024.07.03.601958 ↗