Fylo›ARCADIA›Graph
Hubs
Factor·arcadia

PGM3 protein

Phosphoglucomutase 3; a crucial enzyme for glycosylation, converting GlcNAc-6-phosphate to GlcNAc-1-phosphate. Mutations cause immunodeficiency with recurrent infections and morphological defects. Top structural hit to a Ciona protein with high similarity.

Confidence
90%
active

Source

Ciona model selection and gene prioritization

Connections (2)

PGM3 is essential for immune developmentAssociation
PGM3 inhibition induces cancer cell apoptosisAssociation