Fylo›NASA›Graph
Hubs
Association·nasa

Unique and common DEGs differ for suborbital and orbital flight

Association describing that some genes are differentially expressed only in suborbital spaceflight, while others overlap with long-term orbital transcriptomes, reflecting both qualitative and quantitative differences in gene regulation.

Confidence
80%
active

Evidence Quote

“We identified a set of genes that were absent in long-haul orbital spaceflight ... while others are commonly represented.”

Relationship

Genes uniquely differentially expressed in suborbital spaceflight differentially expressed Genes commonly represented in orbital spaceflight transcriptomes

Arguments

Genes uniquely differentially expressed in suborbital spaceflightsubject
Genes commonly represented in orbital spaceflight transcriptomesobject

Connections (4)

Inference chain for environment- and phase-specific plant transcriptomic responses in spaceInferenceChain
Spaceflight alters plant gene expressionAssociation
Experimental pipeline and hardware enable rapid transcriptomic profilingInferenceChain
Organ- and context-dependent plant transcriptome responses to spaceflightInferenceChain

Evidence

“Citation to Npj Microgravity 2023 meta-analysis of Arabidopsis plant transcriptome response to space flight and microgravity.”

Barker, R. & et al. (2023). Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome link ↗

“Citation to iScience 2022 paper on transcriptomic studies elucidating plant adaptation to spaceflight and simulated space environments.”

Manzano, A. et al. (2022). Recent transcriptomic studies to elucidate the plant adaptive response to spaceflight and to simulated space environments link ↗

“Citation to Astrobiology 2012 paper on unique transcriptome responses to spaceflight.”

Paul, A.-L. & et al. (2012). Spaceflight transcriptomes: unique responses to a novel environment link ↗

“Citation to Frontiers in Plant Science 2021 paper on epigenomic regulators (elongator complex subunit 2 and methyltransferase 1) in Arabidopsis spaceflight response.”

Paul, A.-L. et al. (2021). Epigenomic regulators elongator complex subunit 2 and methyltransferase 1 differentially condition the space-flight response in Arabidopsis link ↗