Association·nasa
Pr_FHL intermediate state crucial for system kinetics in model
Modeling demonstrates that introducing an intermediate state representing Pr_FHL complex is essential to recapitulate the slow switching-off of luciferase expression, as shown in simulated and experimental kinetic curves.
Confidence
90%
active
Evidence Quote
“Simulation of different stability of Pr_FHL intermediate state affects system kinetics”
Relationship
Pr_FHL intermediate state determines modelled kinetics of luciferase signal shut-off