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N-end rule pathway regulates hypoxia response

Claim that N-end rule pathway activity regulates the homeostatic response of plants to hypoxia.

Confidence
90%
active

Evidence Quote

“N-end rule pathway regulates hypoxia response in plants”

Relationship

N-end rule pathway activity regulates Homeostatic response to hypoxia in plants

Arguments

N-end rule pathway activitysubject
Homeostatic response to hypoxia in plantsobject

Connections (4)

Molecular mechanisms regulating Arabidopsis stress responsesInferenceChain
Spaceflight alters plant gene expressionAssociation
Gene regulation and metabolic adaptation in plant hypoxic stressInferenceChain
Reasoning on plant responses to low-oxygen and spaceflight-induced stressInferenceChain

Evidence

“Reference to 2011 Nature paper on the role of the N-end rule pathway in plant oxygen sensing.”

Licausi, F. (2011). Oxygen sensing in plants is mediated by an N-end rule pathway for protein destabilization doi:10.1038/nature10536 ↗

“Licausi et al. (2011b) provide evidence that hypoxia-responsive genes in Arabidopsis are regulated by various subsets of transcription factors and miRNAs, with the composition determined by oxygen availability.”

Licausi, F. et al. (2011). Hypoxia responsive gene expression is mediated by various subsets of transcription factors and miRNAs that are determined by the actual oxygen availability doi:10.1111/j.1469-8137.2010.03451.x ↗

“Liu et al. (2005) present global transcriptional profiling that provides comprehensive insights into the plant hypoxic response mechanisms in Arabidopsis.”

Liu, F. et al. (2005). Global transcription profiling reveals comprehensive insights into hypoxic response in Arabidopsis doi:10.1104/pp.104.055475 ↗

“Miyashita & Good (2008) show that the GABA shunt contributes to alanine accumulation in Arabidopsis roots in response to hypoxia.”

Miyashita, Y. & Good, A. G. (2008). Contribution of the GABA shunt to hypoxia-induced alanine accumulation in roots of Arabidopsis thaliana doi:10.1093/pcp/pcm171 ↗