Association·nasa
Histone and bHLH genes are differentially expressed uniquely in suborbital flight
Claim that histone protein/modification genes are downregulated and bHLH transcription factor genes exhibit distinct patterns between roots and leaves in suborbital flight, and are not differentially expressed in orbital environments.
Confidence
80%
active
Evidence Quote
“Genes of histone proteins and enzymes...mostly repressed at F3...superfamily of bHLH transcription factors...repressed in roots and induced in leaves...not typical of sustained orbital habitats.”
Relationship
Histone genes and modifying enzymes unique regulation Basic helix-loop-helix (bHLH) transcription factor genes
Arguments
Connections (3)
Evidence
“Citation to BMC Genomics 2019 paper on organ-specific changes in DNA methylation and gene expression in spaceflight Arabidopsis.”
Zhou, M. et al. (2019). Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana link ↗
“Citation to Npj Microgravity 2019 paper on alternative splicing in Arabidopsis seedlings during spaceflight.”
Beisel, N. S. et al. (2019). Spaceflight-induced alternative splicing during seedling development in Arabidopsis thaliana link ↗
“Citation to BMC Plant Biology 2013 paper on organ-specific Arabidopsis transcriptome remodeling in response to spaceflight.”
Paul, A.-L. et al. (2013). Organ-specific remodeling of the Arabidopsis transcriptome in response to spaceflight link ↗
“Citation to Frontiers in Plant Science 2020 paper on root skewing-associated genes impacting Arabidopsis spaceflight response.”
Califar, B. et al. (2020). Root skewing-associated genes impact the spaceflight response of Arabidopsis thaliana link ↗