Association·nasa
Distinct HSP/HSF gene regulation patterns in suborbital vs orbital flight
Claim that the expression patterns of heat shock protein (HSP) and heat shock factor (HSF) gene families differ between suborbital and orbital spaceflight, with HSP20s strongly induced only in suborbital.
Confidence
80%
active
Evidence Quote
“Most of repressed HSP genes belonged to HSP70 and HSP90 subfamilies...Greater consistency is seen among the small HSPs (HSP20s)... induced in suborbital flight. The HSP20 family is not highly represented in the orbital spaceflight transcriptomes...”
Relationship
Heat shock protein (HSP) genes differs in pattern Genes commonly represented in orbital spaceflight transcriptomes
Arguments
Connections (6)
Inference chain for environment- and phase-specific plant transcriptomic responses in spaceInferenceChain
Spaceflight alters plant gene expressionAssociation
Experimental pipeline and hardware enable rapid transcriptomic profilingInferenceChain
Organ- and context-dependent plant transcriptome responses to spaceflightInferenceChain
Heat shock proteins, chaperones, and ROS response mediate plant adaptation in spaceflightInferenceChain
Bioinformatic workflows underpin phase- and organ-enriched transcriptomic discoveryInferenceChain
Evidence
“Citation to BMC Plant Biology 2013 paper on organ-specific Arabidopsis transcriptome remodeling in response to spaceflight.”
Paul, A.-L. et al. (2013). Organ-specific remodeling of the Arabidopsis transcriptome in response to spaceflight link ↗
“Citation to Astrobiology 2015 paper on proteome alterations in Arabidopsis induced by spaceflight.”
Ferl, R. J. et al. (2015). Spaceflight induces specific alterations in the proteomes of Arabidopsis link ↗
“Citation to Npj Microgravity 2023 meta-analysis of Arabidopsis plant transcriptome response to space flight and microgravity.”
Barker, R. & et al. (2023). Meta-analysis of the space flight and microgravity response of the Arabidopsis plant transcriptome link ↗
“Citation to Paul, A.-L. 2013 Am. J. Bot. study on heat shock protein and molecular chaperone gene engagement in Arabidopsis thaliana tissue culture cells exposed to spaceflight.”
Spaceflight engages heat shock protein and other molecular chaperone genes in tissue culture cells of Arabidopsis thaliana