Association·arcadia
Protein conservation patterns vary among genes and species
Claim that gene families and proteins differ in their conservation patterns relative to humans, with some closely following phylogeny and others showing deeply conserved or counterintuitive similarity.
Confidence
80%
active
Evidence Quote
“Gene families and proteins differ widely in conservation patterns relative to humans”
Relationship
Molecular conservation varies by gene family
Arguments
Connections (2)
Evidence
“Reference for strategies using evolutionary analysis to propose new model organisms.”
York R & Patton A (2024). Leveraging evolution to identify novel organismal models of human biology doi:10.5281/ZENODO.14425432 ↗
“Evidence summarizing the EukProt database as a comprehensive resource for genome-scale predicted proteins across eukaryotic diversity.”
(2022). EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes doi:10.24072/pcjournal.173 ↗
“Evidence summarizing the cogeqc R/Bioconductor package for assessing data quality and results in comparative genomics.”
Almeida‐Silva F & Van de Peer Y (2023). Assessing the quality of comparative genomics data and results with the cogeqc R/Bioconductor package doi:10.1111/2041-210x.14243 ↗
“Evidence summarizing evolutionary approaches to identify novel organismal models of human biology.”
York R & Patton A (2024). Leveraging evolution to identify novel organismal models of human biology doi:10.5281/ZENODO.14425432 ↗