Association·arcadia

Nucleotide- and target-binding clefts are key actin structural features

Nucleotide-binding cleft binds ATP; target-binding cleft important for binding actin-binding proteins—both are notable actin structural features.

Confidence
70%
active

Evidence Quote

Nucleotide-binding cleft where ATP is typically bound and target-binding cleft are important actin features

Relationship

nucleotide binding cleft features target binding cleft

Evidence

Reference on actin gene family and isoform function

(2010). The actin gene family: Function follows isoform doi:10.1002/cm.20475