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Factor·arcadia

MRGPRX2 receptor

Mas-related G-protein-coupled receptor X2 (MRGPRX2), the primary molecular target of compound 48/80 and substance P for mast cell activation.

Confidence
90%
active

Source

Audrey Bell et al. (2025). Can compound 48/80 be used for safe mast cell degranulation assays? doi:10.57844/arcadia-3207-4695 ↗

Connections (1)

Mechanism of 48/80 toxicity is unrelated to MRGPRX2Association