Association·arcadia
Modification-aware sequencing methods aid detection of modified DNA
Claim that new sequencing technologies (e.g., REMoDE, mEnrich-seq, Nanopore, LC-MS/MS) can support detection and characterization of modified DNA in microbial communities.
Confidence
80%
active
Evidence Quote
“Modification-aware sequencing methods can help detect modified DNA.”
Relationship
Modification-aware sequencing methods enables detection Serratia modif genome
Arguments
Connections (3)
Evidence
“Study describing the REMoDE DNA enrichment method for metagenomic sequencing”
Enam SU et al. (2023). Restriction Endonuclease-Based Modification-Dependent Enrichment (REMoDE) of DNA for Metagenomic Sequencing doi:10.1128/aem.01670-22 ↗
“Preprint describing mEnrich-seq for methylation-guided enrichment sequencing in microbiome studies”
Cao L et al. (2022). mEnrich-seq: Methylation-guided enrichment sequencing of bacterial taxa of interest from microbiome doi:10.1101/2022.11.07.515285 ↗
“Evidence demonstrating REMoDE (Restriction Endonuclease-Based Modification-Dependent Enrichment) as a method to enrich DNA based on modification for metagenomic sequencing, as described by Enam et al. (2023).”
Enam SU et al. (2023). Restriction Endonuclease-Based Modification-Dependent Enrichment (REMoDE) of DNA for Metagenomic Sequencing doi:10.1128/aem.01670-22 ↗
“Evidence that mEnrich-seq is a methylation-guided enrichment sequencing method for bacterial taxa of interest, as described by Cao et al. (2022).”
Cao L et al. (2022). mEnrich-seq: Methylation-guided enrichment sequencing of bacterial taxa of interest from microbiome doi:10.1101/2022.11.07.515285 ↗