KLK5 and KLK7 dual inhibition ameliorates Netherton syndrome and atopic dermatitis — ARCADIA Knowledge Graph

ReasoningCheckpoint·arcadia

KLK5 and KLK7 dual inhibition ameliorates Netherton syndrome and atopic dermatitis

Dual antibody inhibition of KLK5 and KLK7 reduces protease-mediated skin barrier damage and inflammation in skin diseases, indicating key pathogenic roles.

Confidence
90%
◑provedactive

Part of Chain

Kallikrein-mediated skin barrier dysfunction and inflammation pathway