Factor·arcadia

Immune development and T cell function

The process by which the immune system develops and functional T cells are generated; impaired by defects in glycosylation such as loss of PGM3.

Confidence
80%
active

Source

Stray-Pedersen A et al. (2014). PGM3 Mutations Cause a Congenital Disorder of Glycosylation with Severe Immunodeficiency and Skeletal Dysplasia doi:10.1016/j.ajhg.2014.05.007