Host adaptation of retroelement-derived capsid proteins in animals

This reasoning chain explains how retroelement-derived capsid proteins, such as Arc and PEG10, have been domesticated in animal genomes to mediate intercellular RNA transfer and other host functions, exemplifying broad host adaptation of viral-origin proteins. The mechanism is inferred by analogy to retrotransposon Gag domains and observed fusion with novel accessory domains in venomous animals.

Reasoning Steps (2)

Source

Connections (2)