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Gene family sharing decays with phylogenetic distance

Claim that the number of gene families shared with humans decreases as a species' phylogenetic distance from humans increases, though substantial variation and exceptions exist.

Confidence
90%
active

Evidence Quote

“Number of gene families shared with humans decreases with phylogenetic distance, with exceptions”

Relationship

gene family decays with distance Phylogenetic distance

Arguments

Phylogenetic distanceobject

Connections (2)

Partitioning sources of molecular conservation variationInferenceChain
Structural similarity often diverges from sequence similarityAssociation

Evidence

“Evidence summarizing the EukProt database as a comprehensive resource for genome-scale predicted proteins across eukaryotic diversity.”

(2022). EukProt: A database of genome-scale predicted proteins across the diversity of eukaryotes doi:10.24072/pcjournal.173 ↗

“Evidence summarizing NovelTree as a highly parallelized tool for phylogenomic inference.”

Celebi FM et al. (2024). NovelTree: Highly parallelized phylogenomic inference doi:10.57844/ARCADIA-Z08X-V798 ↗

“Evidence summarizing OrthoFinder as a method for phylogenetic orthology inference in comparative genomics.”

Emms DM & Kelly S (2019). OrthoFinder: phylogenetic orthology inference for comparative genomics doi:10.1186/s13059-019-1832-y ↗

“Evidence summarizing OrthoFinder as improving orthogroup inference accuracy by solving biases in whole genome comparisons.”

Emms DM & Kelly S (2015). OrthoFinder: solving fundamental biases in whole genome comparisons dramatically improves orthogroup inference accuracy doi:10.1186/s13059-015-0721-2 ↗

“Evidence summarizing the availability of predicted genes from the Amblyomma americanum draft genome assembly.”

Celebi FM et al. (2024). Predicted genes from the Amblyomma americanum draft genome assembly doi:10.57844/ARCADIA-9602-3351 ↗