Association·arcadia

Compact clusters indicate high within-cluster structural similarity

Claim that high within-cluster TM-score (‘compactness’) corresponds to proteins being structurally similar within Leiden clusters (e.g., LC11 and LC12).

Confidence
90%
active

Evidence Quote

“Clusters with higher within-cluster TM-score (compactness) are structurally similar.”

Relationship

MAPK10 structural cluster compactness correlates Leiden Cluster 11 (LC11) - plant MAPK10-like proteins

Arguments

MAPK10 structural cluster compactnesssubject
Leiden Cluster 11 (LC11) - plant MAPK10-like proteinsobject

Connections (4)

Reasoning on interactive clustering and exploratory analysis of MAPK10 protein familyInferenceChain
Structural similarity often diverges from sequence similarityAssociation
Limits and advantages of structural clustering in ProteinCartographyInferenceChain
Protein structure is substantially more conserved than sequenceInferenceChain