Accessory sequence clusters are species- and toxin-specific — ARCADIA Knowledge Graph

InferenceChain·arcadia

Accessory sequence clusters are species- and toxin-specific

Reasoning chain synthesizing evidence that accessory sequence clusters mostly correspond to individual species and toxins with limited cross-species or cross-toxin convergence, supported by weak functional annotation and cluster distribution patterns.

Confidence
85%
◑partialactivecomplexity: mid

Reasoning Steps (3)

Limitations of Pfam annotation for accessory sequencesStep 1
Accessory sequence clusters mostly species- and toxin-specificStep 2
Tick accessory sequences conserved within ticksStep 3

Source

Synthesis for current paper

Connections (1)

Length outliers indicate gene fusion in venom proteinsAssociation