Association·nasa

Spaceflight triggers enrichment of ion transport and stress protein interaction networks

Protein-protein network analysis of spaceflight DEGs reveals enrichment in ion transport, chaperone activity, heat shock, and protein ubiquitinylation/proteasome functions.

Confidence
80%
active

Evidence Quote

Spaceflight DEGs enriched for ion transport, chaperone, heat shock, and ubiquitinylation networks

Relationship

protein protein network enrichment enriches Ion transport processes

Evidence

Reference to automated method for molecular complex detection in protein networks

An automated method for finding molecular complexes in large protein interaction networks

Reference to STRING v11 protein–protein association network resource

STRING v11: protein–protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets

Reference to BioGRID as a general repository for protein-protein interaction datasets

BioGRID: a general repository for interaction datasets

Reference to OmniPath resources for signaling pathway curation

OmniPath: guidelines and gateway for literature-curated signaling pathway resources

Reference to a scored human protein-protein interaction network

A scored human protein-protein interaction network to catalyze genomic interpretation