Association·nasa
Spaceflight DEGs are enriched for key biological processes
Spaceflight-related differentially expressed genes (DEGs) from BRIC experiments show Gene Ontology enrichment for tropisms, stomatal function, karrikin response, regionalization, oxidative stress, heat shock, cell wall dynamics, and hypoxia.
Confidence
90%
active
Evidence Quote
“Spaceflight DEGs are enriched for tropism, stomatal function, karrikin response, heat shock, cell wall, hypoxia, and others”
Relationship
spaceflight DEGs enriches GO term enrichment
Arguments
Connections (2)
Evidence
“Study examining Arabidopsis transcriptomes under spaceflight conditions”
Paul, A. L. & et al. (2012). Spaceflight transcriptomes: unique responses to a novel environment doi:10.1089/ast.2011.0696 ↗
“Study examining transcriptomic variation and oxidative stress signatures in different Arabidopsis ecotypes during spaceflight”
Choi, W. G. et al. (2019). Variation in the transcriptome of different ecotypes of Arabidopsis thaliana reveals signatures of oxidative stress in plant responses to spaceflight doi:10.1002/ajb2.1236 ↗
“Study using combined proteomic and transcriptomic analyses to examine novel regulatory responses in Arabidopsis seedlings induced by spaceflight”
Kruse, C. P. S. & et al. (2020). Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses doi:10.1186/s12870-020-02447-2 ↗
“Reference to Metascape analysis platform for systems-level datasets”
(2019). Metascape provides a biologist-oriented resource for the analysis of systems-level datasets doi:10.1038/s41467-019-09234-6 ↗
“Reference to DAVID web server for functional enrichment and annotation of gene lists”
(2022). DAVID: a web server for functional enrichment analysis and functional annotation of gene lists (2021 update) doi:10.1093/nar/gkac194 ↗