Association·nasa
SKU5 acts upstream of TOR stress-responsive signaling in spaceflight response
Claim that SKU5 acts upstream of the central TOR signaling pathway in both short- and long-term spaceflight responses, influencing stress-responsive cascades.
Confidence
70%
active
Evidence Quote
“These data collectively support the hypothesis that SKU5 acts upstream of centralized stress-responsive TOR signaling in its contribution to both short- and long-term spaceflight responses.”
Relationship
Platform and genotype context regulates TOR (Target of Rapamycin) signaling
Evidence
“Reference describing SKU5 as a GPI-anchored glycoprotein for root growth”
(2002). The Arabidopsis SKU5 gene encodes an extracellular glycosyl phosphatidylinositol-anchored glycoprotein involved in directional root growth
“Study of gravity-specific calcium signaling in Arabidopsis using parabolic flight”
Toyota M et al. (2013). Analyses of a gravistimulation-specific Ca2+ signature in Arabidopsis using parabolic flights