Heat shock response dominates transcriptional induction — NASA Knowledge Graph

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Heat shock response dominates transcriptional induction

The largest and most strongly induced gene category under spaceflight are heat shock response genes, comprising half of all >5-fold changes and most of the very strongest inductions. This suggests acute proteotoxic or misfolded protein stress is sensed by cultured Arabidopsis cells in microgravity.

Confidence
80%
◑partialactive

Part of Chain

Spaceflight alters expression of stress and regulatory genes in Arabidopsis cells