Association·nasa

Central signaling regulates spaceflight stress responses

Claim that central signaling mechanisms (including TOR, light, defense responses) coordinate the plant's transcriptomic and physiological response under altered gravity.

Confidence
80%
active

Evidence Quote

We have hypothesized that this central signaling regulates spaceflight-induced stress responses.

Relationship

central signaling regulates Platform and genotype context

Evidence

Reference on ABP1-TMK auxin receptor complex and signal activation in Arabidopsis

(2014). Cell surface ABP1-TMK auxin-sensing complex activates ROP GTPase signaling

Study on role of HSFA2 in Arabidopsis cell adaptation to spaceflight

(2019). HSFA2 functions in the physiological adaptation of undifferentiated plant cells to spaceflight

Reference for ARG1 gene function in Arabidopsis cell adaptation to spaceflight

(2017). ARG1 functions in the physiological adaptation of undifferentiated plant cells to spaceflight

Reference for heat shock protein and chaperone gene activation during Arabidopsis spaceflight

(2013). Spaceflight engages heat shock protein and other molecular chaperone genes in tissue culture cells of Arabidopsis thaliana

Reference for GPI-anchored proteins in Arabidopsis signaling

Zhou K (2019). Glycosylphosphatidylinositol-anchored proteins in Arabidopsis and one of their common roles in signaling transduction doi:10.3389/fpls.2019.01022

Reference for spaceflight induced DNA methylation and gene expression changes in Arabidopsis organs

Zhou M et al. (2019). Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana doi:10.1186/s12864-019-5588-4