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Antagonistic regulation of shoot orientation by TAC1 and LAZY1

Synthesizes evidence and genetic interactions indicating that TAC1 and LAZY1 act in opposition to control lateral shoot orientation in Arabidopsis: TAC1 promotes outward orientation while LAZY1 promotes upward orientation through distinct but overlapping pathways. Epistasis and hormone level findings further suggest complex regulatory hierarchy.

Confidence
85%
◑partialactivecomplexity: low

Reasoning Steps (4)

TAC1 and LAZY1 have overlapping expression patternsStep 1
Epistasis of lazy1 over tac1 in double mutantsStep 2
Distinct effects on gravitropic responseStep 3
Hormone and transcriptome context of TAC1 and LAZY1 mutantsStep 4

Source

Synthesis for current paper

Connections (5)

TAC1 promotes outward lateral shoot orientationAssociation
LAZY1 promotes upward shoot orientation via auxin transportAssociation
TAC1 might negatively regulate LAZY1Association
lazy1 mutant phenotype is epistatic to tac1Association
LAZY1 acts upstream of auxin transportAssociation