ReasoningCheckpoint·arcadia

Validity of Chlamydomonas as disease model

Sequence and structural homology between human SPEF2/DNALI1 and Chlamydomonas orthologs supports the use of Chlamydomonas mutants as valid models for human SPGF disorders.

Confidence
90%
◑provedactive

Part of Chain

Mechanistic reasoning for drug restoration of motility in SPGF models