Association·arcadia
Taxonomic bias in AFDB covaries with pLDDT and impacts Foldseek applications
Claim that taxonomic bias in the AlphaFold database covaries with the mean pLDDT scores and influences downstream applications using pLDDT, such as Foldseek clustering.
Confidence
80%
active
Evidence Quote
“Taxonomic biases covary with AlphaFold’s pLDDT measurements and can impact downstream applications of AlphaFold that rely on pLDDT, such as Foldseek.”
Relationship
Phylogenetic bias covaries pLDDT