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Solid state samples yield stronger Raman signal

Claim that solid state biological samples yield much higher Raman signals than liquid cultures, likely due to lower background and higher density.

Confidence
90%
active

Evidence Quote

“Biological samples give much more signal when in a solid state than liquid cultures, likely because of lower background and higher density.”

Relationship

Solid state samples yield stronger signal increases High-dimensional compositional data acquisition

Arguments

Solid state samples yield stronger signalsubject
High-dimensional compositional data acquisitionobject

Connections (4)

Reasoning about system performance limits and improvement avenues in OpenRAMANInferenceChain
Microchamber components enable microscopyAssociation
Raman enables metabolic and single-cell functional studiesInferenceChain
Literature studies support methodological choices in Raman phenotypingInferenceChain

Evidence

“Reference on the use of mirrored SS substrate to improve Raman signal in cells/tissues.”

Lewis AT et al. (2016). Mirrored stainless steel substrate provides improved signal for Raman spectroscopy of tissue and cells doi:10.1002/jrs.4980 ↗