Factor·arcadia
Reconstructed ancestral protein sequences
Protein sequences that have been computationally reconstructed to represent ancestral forms, used to evaluate language model understanding of evolution.
Confidence
80%
active
Source
Evan Kiefl et al. (2025). Do protein language models understand evolution? Mixed evidence from ancestral sequences and ESM2 doi:10.57844/arcadia-5cwu-spn8 ↗