ReasoningCheckpoint·arcadia
Poxvirus encodes secreted IFN-γ receptor homologs
Poxviruses produce secreted homologs of the interferon-gamma receptor (e.g., M-T7) that bind IFN-γ and inhibit its immune signaling, acting as critical virulence factors.
Confidence
90%
◑provedactive
Part of Chain
Poxvirus mediated IFN-γ immune evasion mechanism