InferenceChain·arcadia

Phylogenetic HGT inference faces methodological and biological limitations

Reasoning chain explaining trade-offs and challenges in inferring horizontal gene transfer (HGT) from phylogenetic methods, including methodological sources of gene tree discordance and biological confounders.

Confidence
80%
◑partialactivecomplexity: mid

Reasoning Steps (2)

Gene tree discordance from multiple causesStep 1
Phylogenetic scale helps discriminate between HGT and ILSStep 2

Source

Synthesis for current paper

Connections (1)

Phylogenetic methods identify candidate HGT eventsAssociation