Association·arcadia
Phylogenetic biases and non-independence cap model generalizability
Claim that unmitigated phylogenetic bias and non-independence in protein datasets restrict the generalizability of machine learning models for protein prediction and design.
Confidence
90%
active
Evidence Quote
“Unmitigated non-independence and phylogenetic biases ... cap the generalizability of protein prediction and design”
Relationship
Phylogenetic bias decreases Machine learning models for protein design
Connections (3)
Evidence
“Supports claims that integrating phylogenies is essential for comparative biological analyses and controlling bias.”