Association·arcadia
NCKAP1L/HEM1 essential for innate immunity and lymphopoiesis
Claim that NCKAP1L (HEM1) is required for normal innate immune responses and lymphopoiesis, as seen in mice with HEM1 point mutations.
Confidence
80%
active
Evidence Quote
“HEM1/NCKAP1L is essential for lymphopoiesis and innate immunity.”
Relationship
NCKAP1L protein enables Innate immune function and lymphopoiesis
Connections (1)
Evidence
“Reference to Park et al. (2008) on murine Hem1 gene mutation and immunity.”
Park H et al. (2008). A point mutation in the murine Hem1 gene reveals an essential role for Hematopoietic Protein 1 in lymphopoiesis and innate immunity doi:10.1084/jem.20080340 ↗