Maternal expression led to exclusion of several genes — ARCADIA Knowledge Graph

ReasoningCheckpoint·arcadia

Maternal expression led to exclusion of several genes

Expert feedback identified genes with strong maternal expression (e.g. NAXE, GAS2L2, DHODH, CWF19L1) as poor candidates for Ciona knockout assays, since maternal transcripts can mask phenotypes in early embryonic development.

Confidence
70%
◑partialactive

Part of Chain

Rationale for gene selection and exclusion in Ciona modeling