Limits of predicting molecular conservation from phylogeny and gene counts | ARCADIA FyloGraph | FyloGraph

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InferenceChain·arcadia

Limits of predicting molecular conservation from phylogeny and gene counts

This reasoning chain explains why Elo ratings for molecular conservation cannot be linearly or simply predicted from phylogenetic distance or gene family counts. It incorporates the observation of substantial variation, extreme outliers, and positive or negative residuals in conservation across taxa and species.

Confidence

80%

◑partialactivecomplexity: mid

Reasoning Steps (3)

Phylogenetic distance alone is insufficient to predict Elo ratingStep 1

Gene family counts explain some but not all Elo rating variationStep 2

Exceptional conservation in specific taxa and speciesStep 3

Source

Synthesis for current paper

Connections (6)

Elo ratings not linearly predicted by phylogenetic distanceAssociation

Certain species have extreme Elo rating outliersAssociation

Vertebrates have higher Elo ratings than other taxaAssociation

Distant species can have Elo ratings like invertebratesAssociation

Regression predicts Elo rating using human gene family countsAssociation

Species with exceptional molecular conservation show positive residualsAssociation