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Kynurenine pathway enzymes upregulated during ant behavioral manipulation

Claim that indoleamine 2,3-dioxygenase and kynurenine 3-monooxygenase enzymes are upregulated in Ophiocordyceps kimflemingiae during the manipulation of ant behavior.

Confidence
80%
active

Evidence Quote

“Indoleamine 2,3-dioxygenase and kynurenine 3-monooxygenase upregulated during behavioral manipulation”

Relationship

Kynurenine pathway enzymes in Ophiocordyceps kimflemingiae upregulated Behavioral manipulation of ants by Ophiocordyceps

Arguments

Kynurenine pathway enzymes in Ophiocordyceps kimflemingiaesubject
Behavioral manipulation of ants by Ophiocordycepsobject

Connections (3)

Reasoning about functional significance of HGT candidate genes in fungal behavioral manipulation and pathogenicityInferenceChain
Sexual size dimorphism is associated with habitat use in Anolis lizardsAssociation
Horizontally transferred genes support host manipulation and pathogenicityInferenceChain

Evidence

“Study investigating gene expression patterns in Ophiocordyceps during host ant behavioral manipulation.”

de Bekker C et al. (2015). Gene expression during zombie ant biting behavior reflects the complexity underlying fungal parasitic behavioral manipulation doi:10.1186/s12864-015-1812-x ↗

“Evidence line summarizing de Bekker et al. (2015) on gene expression underlying behavioral manipulation in ants by parasitic fungi.”

de Bekker C et al. (2015). Gene expression during zombie ant biting behavior reflects the complexity underlying fungal parasitic behavioral manipulation doi:10.1186/s12864-015-1812-x ↗

“Reference covering the impact of kynurenines on CNS disorders and the potential for neuroprotective strategies.”

(2009). The role of kynurenines in disorders of the central nervous system: Possibilities for neuroprotection doi:10.1016/j.jns.2009.02.326 ↗