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InferenceChain·arcadia

Integrating literature and annotation for Ras GTPase clustering

Explains how overlaying established Ras superfamily annotations and major literature with ProteinCartography cluster results strengthens the claim that clusters correspond to functionally distinct Ras subfamilies.

Confidence

80%

◑partialactivecomplexity: mid

Reasoning Steps (2)

Classical Ras superfamily definitions from literatureStep 1

Annotation overlay analysis supports subfamily groupingStep 2

Source

Synthesis for current paper

Connections (2)

Leiden clusters group Ras GTPase subfamiliesAssociation

Ras GTPase subfamilies cluster togetherAssociation