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Inference chain for AMR genotype-phenotype associations — ARCADIA Knowledge Graph

InferenceChain·arcadia

Inference chain for AMR genotype-phenotype associations

Logical synthesis linking non-silent variants in known AMR genes to observed resistance phenotypes, highlighting significant and insignificant associations.

Confidence

90%

◑partialactivecomplexity: mid

Reasoning Steps (3)

Significant association of tetA non-silent variants with tetracycline resistanceStep 1

Lack of significant association between catA1 variants and chloramphenicol resistanceStep 2

Mixed phenotypic resistance with dfrD variantsStep 3

Source

Synthesis for current paper

Connections (3)

Non-silent variants in tetA genes associated with tetracycline resistanceAssociation

Non-silent variants in catA1 gene and chloramphenicol resistanceAssociation

Non-silent variants in dfrD gene and trimethoprim resistanceAssociation