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Horizontal gene transfer (HGT) enables acquisition of novel gene functions

Claim that HGT is the exchange of DNA between species, enabling organisms to gain new gene functions and resulting in genome novelty and rapid adaptation.

Confidence
100%
active

Evidence Quote

“Horizontal gene transfer (HGT) is the exchange of DNA between species. It can lead to the acquisition of new gene functions, so finding HGT events can reveal genome novelty.”

Relationship

Horizontal gene transfer event enables Novel gene function in genome

Arguments

Horizontal gene transfer eventsubject
Novel gene function in genomeobject

Connections (1)

Plutella xylostella may acquire N protein via parasite-to-host HGTAssociation

Evidence

“DOI reference to review on HGT's role in evolution”

(2015). Horizontal gene transfer: building the web of life doi:10.1038/nrg3962 ↗

“DOI reference to study on functional HGT to eukaryotes”

Husnik F & McCutcheon JP (2017). Functional horizontal gene transfer from bacteria to eukaryotes doi:10.1038/nrmicro.2017.137 ↗

“DOI reference to review on HGT and bacterial adaptation”

Arnold BJ et al. (2021). Horizontal gene transfer and adaptive evolution in bacteria doi:10.1038/s41579-021-00650-4 ↗

“DOI reference to mechanistic overview on HGT patterns”

Zaneveld JR et al. (2008). Are all horizontal gene transfers created equal? Prospects for mechanism-based studies of HGT patterns doi:10.1099/mic.0.2007/011833-0 ↗

“DOI reference to review on extent of HGT in eukaryotes”

Van Etten J & Bhattacharya D (2020). Horizontal Gene Transfer in Eukaryotes: Not if, but How Much? doi:10.1016/j.tig.2020.08.006 ↗

“DOI reference to review on gene flow mechanisms in archaea”

Wagner A et al. (2017). Mechanisms of gene flow in archaea doi:10.1038/nrmicro.2017.41 ↗

“DOI reference to study contradicting extensive HGT in tardigrade genomes”

No evidence for extensive horizontal gene transfer in the genome of the tardigrade Hypsibius dujardini

“Reference for Copley SD, Dhillon JK. (2002) on LGT and parallel evolution in glutathione pathways”

Copley SD & Dhillon JK (2002). Lateral gene transfer and parallel evolution in the history of glutathione biosynthesis genes doi:10.1186/gb-2002-3-5-research0025 ↗

“Reference for Cote-L’Heureux A et al. (2022) on interdomain LGT events”

Cote-L’Heureux A et al. (2022). Old genes in new places: A taxon-rich analysis of interdomain lateral gene transfer events doi:10.1371/journal.pgen.1010239 ↗

“Reference for Knowles LL et al. (2018) on distinguishing ILS from LGT by phylogenetic scale”

Knowles LL et al. (2018). A matter of phylogenetic scale: Distinguishing incomplete lineage sorting from lateral gene transfer as the cause of gene tree discord in recent versus deep diversification histories doi:10.1002/ajb2.1064 ↗

“Reference for Ravenhall M et al. (2015) review on inference of HGT”

Ravenhall M et al. (2015). Inferring Horizontal Gene Transfer doi:10.1371/journal.pcbi.1004095 ↗

“Reference for (2020) on patterns and impacts of nonvertical evolution in eukaryotes”

(2020). Patterns and impacts of nonvertical evolution in eukaryotes: a paradigm shift doi:10.1111/nyas.14471 ↗

“Evidence line summarizing rapid evolutionary innovation during an Archaean genetic expansion, with relevance to horizontal gene transfer, as shown by David and Alm (2010).”

David LA & Alm EJ (2010). Rapid evolutionary innovation during an Archaean genetic expansion doi:10.1038/nature09649 ↗

“Evidence line summarizing that horizontal gene transfer occurs from bacteria and plants to the arbuscular mycorrhizal fungus Rhizophagus irregularis, as shown by Li et al. (2018).”

Li M et al. (2018). Horizontal Gene Transfer From Bacteria and Plants to the Arbuscular Mycorrhizal Fungus Rhizophagus irregularis doi:10.3389/fpls.2018.00701 ↗