ReasoningCheckpoint·arcadia
Defective glycosylation impairs T cell development
Loss of proper glycosylation (e.g., due to PGM3 deficiency) blocks T cell maturation and function, resulting in combined immune deficiency.
Confidence
70%
◑partialactive
Loss of proper glycosylation (e.g., due to PGM3 deficiency) blocks T cell maturation and function, resulting in combined immune deficiency.