ReasoningCheckpoint·arcadia
Compound 48/80 toxicity in relevant cell lines
Compound 48/80 is confirmed to be toxic in HMC1.2 and RBL-2H3 cells, which are mast cell models relevant to host immune responses, supporting caution in interpreting immunomodulatory assays.
Confidence
70%
◑partialactive
Part of Chain
Tick saliva modulates host immune responses