Cluster annotation quality and taxonomic grouping reflect functional class — ARCADIA Knowledge Graph

Cluster annotation quality and taxonomic grouping reflect functional class

Clusters are made up primarily of a single Ras subfamily and display similar annotation patterns; clusters with generic annotations or mixed taxonomic representation may still share family-wide catalytic functions. Subfamily clusters (e.g., Arf as LC04, Rab with Ran) reinforce that structure-guided clustering recapitulates functional classification.

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