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Capsid proteins interact with and package RNA — ARCADIA Knowledge Graph

Association·arcadia

Capsid proteins interact with and package RNA

Claim that tick-encoded viral capsid proteins, especially RNA nucleocapsids and Gag-Pol, interact with and help package RNA molecules.

Confidence
70%
active

Evidence Quote

“Tick-encoded capsid types are RNA nucleocapsids and retrotransposon Gag-Pol proteins, both interact with and help package RNA molecules.”

Relationship

RNA nucleocapsid capsid packages RNA molecule

Arguments

Gag-Pol protein from LTR-type retrotransposonssubject
Viral capsid proteinobject

Connections (2)

Bracovirus capsid HMM detects capsid in Microplitis demolitorAssociation
Reasoning: Ticks as venomous animals and RNA viral capsid functionInferenceChain

Evidence

“Reference to Pastuzyn et al. (2018) publication on the neuronal gene Arc as a repurposed retrotransposon protein.”

Pastuzyn ED et al. (2018). The Neuronal Gene Arc Encodes a Repurposed Retrotransposon Gag Protein that Mediates Intercellular RNA Transfer doi:10.1016/j.cell.2017.12.024 ↗

“Ding B, Qin Y, Chen M. (2016). Review of nucleocapsid proteins’ functions.”

Ding B et al. (2016). Nucleocapsid proteins: roles beyond viral RNA packaging. doi:10.1002/wrna.1326 ↗

“Luo M, Terrell JR, Mcmanus SA. (2020). Structural study of viral nucleocapsids.”

Luo M et al. (2020). Nucleocapsid Structure of Negative Strand RNA Virus. doi:10.3390/v12080835 ↗